15^th Annual Conference on Dementia and Alzheimers Disease June 25-26, 2020 Abu Dhabi, UAE

Alzheimers disease (AD), also referred to simply as Alzheimer's, is a chronic neurodegenerative disease that usually starts slowly and worsens over time. It is the cause of 60% to 70% of cases of dementia. The most common early symptom is difficulty in remembering recent events short-term memory loss. [As the disease advances, symptoms can include problems with language, disorientation (including easily getting lost), mood swings, loss of motivation, not managing self-care, and behavioral issues. As a person's condition declines, they often withdraw from family and society.  Gradually, bodily functions are lost, ultimately leading to death.

Neurodegenerative diseases cause your brain and nerves to deteriorate over time. They can change your personality and cause confusion. They can also destroy your brain’s tissue and nerves. Some brain diseases, such as Alzheimer’s disease, may develop as you age. They can slowly impair your memory and thought processes. Other diseases, such as Tay-Sachs disease, are genetic and begin at an early age.

The brain is body’s control center. It’s part of the nervous system, which also includes the spinal cord and a large network of nerves and neurons. Together, the nervous system controls everything from your five senses to the muscles throughout your body. When your brain is damaged, it can affect many different things, including your memory, your sensation, and even your personality. Brain disorders include any conditions or disabilities that affect your brain. This includes those conditions that are caused by illness, genetics, or traumatic injury.

Apathy, depression and anxiety are common conditions experienced by people with dementia. They are known as psychological conditions because they can affect a person’s emotional and mental health. Anxiety is more than just feeling stressed or worried. Anxious feelings are a normal reaction to a situation where a person feels under pressure and usually pass once the stressful situation has passed, or the ‘stressor’ is removed. Depression affects how a person feels about themselves. A person may lose interest in work, hobbies and doing things he or she normally enjoys. Some people may lack energy, have difficulty sleeping or sleep more than usual, while some people feel anxious or irritable and find it hard to concentrate.

Parkinson's disease (PD) is a chronic and progressive movement disorder, meaning that symptoms continue and worsen over time. Nearly one million people in the US are living with Parkinson's disease. The cause is unknown, and although there is presently no cure, there are treatment options such as medication and surgery to manage its symptoms.

Schizophrenia is a chronic brain disorder that affects about one percent of the population. When schizophrenia is active, symptoms can include delusions, hallucinations, trouble with thinking and concentration, and lack of motivation. However, when these symptoms are treated, most people with schizophrenia will greatly improve over time.

Autism is a lifelong developmental disability that affects how people perceive the world and interact with others. Autistic people see, hear and feel the world differently to other people. If you are autistic, you are autistic for life autism is not an illness or disease and cannot becured. Often people feel being autistic is a fundamental aspect of their identity. Autism is a spectrum condition. All autistic people share certain difficulties, but being autistic will affect them in different ways. Some autistic people also have learning disabilities, mental health issues or other conditions, meaning people need different levels of support. All people on the autism spectrum learn and develop. With the right sort of support, all can be helped to live a more fulfilling life of their own choosing.

Diagnosing dementia and determining what type it is can be challenging. A diagnosis of dementia requires that at least two core mental functions be impaired enough to interfere with daily living. They are memory, language skills, ability to focus and pay attention, ability to reason, solve problem and visual perception.

There is no cure for dementia, so the chief goals of treatment are to: Maintains quality of life, Enhances cognition, mood and behaviour, Fosters a safe environment, Promotes social engagement, Treatment of cognitive symptoms, Managing behavioural symptoms, pharmacological treatments, non-pharmacological strategies, Dementia friendly Environments.

Animal models have contributed noticeably to these advances and are an indispensable part in the evaluation of therapeutics. This review is an exhaustive study of animal models of dementia and cognitive dysfunction. A thorough Dementia and Alzheimers Disease and critical evaluation of current rodent models of dementia and discussion about their role in drug discovery and development have been carried out.

Dementia is a progressive, irreversible decline in cognition that, by definition, impacts on a patient pre-existing level of functioning. The clinical syndrome of dementia has several aetiologias of which Alzheimer’s disease (AD) is the most common. Drug development in AD is based on evolving pathophysiological theory. Disease modifying approaches include the targeting of amyloid processing, aggregation of tau, insulin signaling, neuroinflammation and neurotransmitter dysfunction, with efforts thus far yielding abandoned hopes and ongoing promise. Reflecting its dominance on the pathophysiological stage the amyloid cascade is central to many of the emerging drug therapies.

Epidemiological studies show that, worldwide, the number of people aged over 65 will increase substantially in the next decades and that a considerable proportion of this population will develop dementia. Ample evidence shows that ageing is associated with a high rate of painful conditions, irrespective of cognitive status. The number of patients with dementia who will experience painful conditions is therefore likely to increase.

The goal of much of the research activity in dementia is to develop interventions for 'treatment' or even 'cure'. The classical bench to bedside paradigm has been disappointing in dementia. There is a long list of putative dementia treatment compounds with favorable pre-clinical and early phase trial data that have been neutral or even potentially harmful when assessed in phase III studies. Lewy body dementia is a common but frequently under diagnosed cause of dementia often mistaken for the more familiar entity of Alzheimer disease. Clinically the distinction is important, because it can have profound implications for management. The diagnosis of Lewy body dementia has important implications. It is associated with a high incidence of neuroleptic sensitivity, necessitating great caution in the use of these common antipsychotic agents. Early studies indicate cholinesterase inhibitors can be beneficial for treating the hallucinations and behavior disturbances that afflict these patients and might also improve cognition.

A psychiatric disorder may also cause physical symptoms, such as a headache, back pain, or stomach pain. If you’re being evaluated for a psychiatric disorder, be sure to tell your doctor about any physical symptoms you’re having, including unexplained aches and pains. Mental health nursing or psychiatry nursing is the speciality of nursing that cares for people of all ages with mental distress or illness such as schizophrenia, bipolar disorder, depression, psychosis it is a stressful and emotionally draining job as well as a rewarding job for once career.

Public Health is outlined because the science of protective the security and up the health of communities through education, political, and analysis for wellness and injury hindrance. The definition of public health is completely different for each person. whether or not you wish to crunch numbers, conduct laboratory or field analysis, formulate policy, or work directly with folks to assist improve their health, there's an area for you within the field of public health. Being a public professional person allows you to figure round the world, address health issues of communities as an entire, and influence policies that have an effect on the health of societies.

Neurosurgery is a medical specialty concerned with the prevention, diagnosis and treatment of patients with injuries or diseases/disorders of the brain, spinal cord and peripheral nerves  all inner parts of the body. A physician who specializes in neurosurgery is known as Neurosurgeon. Medically trained neurosurgical specialists help patients suffering from back and neck pain as well as other illnesses ranging from trigeminal neuralgia to head injury and Parkinson's disease.

A stroke is a "brain attack". It can appear to anyone at any time when poor blood flow to an area of brain and results in cell death. When this happens brain cells are dispossessed of oxygen and begin to die. When brain cells die during a stroke it controls ability by that area of the brain such as memory and muscle control is lost

Vascular Dementia is that the second most regular reason for insanity once Alzheimer's Diseases. Vascular changes that begin in mind territories that assume a key half in putt away and sick information could cause memory misfortune that appears particularly like Alzheimer's disease sickness. Vascular dementedness may be a decrease in intuition skills caused by conditions that sq.or diminish blood stream to the brain, denying mind cells of fundamental oxygen and supplements. Deficient blood stream can harm and, in the end, dead cells anyplace in the body. The mind has one in all the body's richest systems of veins and is especially helpless. In tube insanity, changes in speculation talents currently so happen suddenly following strokes that sq. important neural structure veins. A developing variety of specialists lean toward the expression "Vascular cognitive Impairment (VCI)" to "vascular dementia”. A few examinations have discovered that vascular changes and different neural structure irregularities could associate in ways in which improve the chance of dementedness finding. The analysis of dementia or mild psychological electric resistance is affirmed by neurocognitive testing, which has some hours of composed or mechanized tests that offer purpose by purpose assessment of reasoning skills, for instance, judgment, arranging, crucial thinking, thinking and memory.